The Rostral Ventrolateral Medulla Input to Central Amygdala Regulates Anxiety‐Like Behaviors in Mice for Chronic Light Exposure

CEA (Central amygdalar nucleus) MBA:536 projects to MY (Medulla) MBA:354 · Mouse

Injection of a retrograde EGFP-expressing AAV into the RVLM produced labelled neurons in the central amygdala, indicating a descending CeA input to the RVLM and thus a reciprocal connection.

Fig. 2E–L (panel K)

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

NTS (Nucleus of the solitary tract) MBA:651 projects to MY (Medulla) MBA:354 · Mouse

Retrograde AAV-EGFP injected into the RVLM produced retrogradely labelled neurons in the nucleus of the solitary tract.

Fig. 2E–L

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

PVH (Paraventricular hypothalamic nucleus) MBA:38 projects to MY (Medulla) MBA:354 · Mouse

Retrograde AAV-EGFP injected into the RVLM labelled neurons in the paraventricular hypothalamic nucleus.

Fig. 2E–L

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

LC (Locus ceruleus) MBA:147 projects to MY (Medulla) MBA:354 · Mouse

Retrograde AAV-EGFP injected into the RVLM labelled neurons in the locus coeruleus.

Fig. 2E–L

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

NTS (Nucleus of the solitary tract) MBA:651 projects to CEA (Central amygdalar nucleus) MBA:536 · Mouse

After retrograde EGFP-expressing AAV was injected into the CeA, retrogradely labelled neurons were also seen in the nucleus of the solitary tract of the medulla.

Fig. 2C

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

MY (Medulla) MBA:354 projects to CEA (Central amygdalar nucleus) MBA:536 · Mouse

A retrograde AAV expressing EGFP placed in the CeA produced labelled cell bodies in the rostral ventrolateral medulla, identifying CeA-projecting RVLM neurons. A second, dual-virus approach (retrograde Cre into CeA plus Cre-dependent EGFP into RVLM) again labelled RVLM neurons that project to the CeA.

Fig. 2B–D; Fig. 3A,D

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.