Whole-Brain Map of Long-Range Monosynaptic Inputs to Different Cell Types in the Amygdala of the Mouse

MB (Midbrain) MBA:313 synapses onto CEAl PKC-delta-expressing neurons nt-g513b58b0y · Mouse

Midbrain neurons, including dense labelling in the superior colliculus, provided monosynaptic input to CeA PKC-δ+ neurons.

Fig. 4B; Fig. 6D

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

CP (Caudoputamen) MBA:672 synapses onto CEAl PKC-delta-expressing neurons nt-g513b58b0y · Mouse

Rabies tracing from CeA PKC-δ+ starters densely labelled input cells in the caudate-putamen.

Fig. 4B-C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

Isocortex MBA:315 synapses onto CEAl PKC-delta-expressing neurons nt-g513b58b0y · Mouse

Isocortex provided inputs to CeA PKC-δ+ neurons, a smaller share than to SST+ neurons.

Fig. 6D

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

PVT (Paraventricular nucleus of the thalamus) MBA:149 synapses onto BLA glutamatergic principal neurons nt-wprma5fcrr · Mouse

Paraventricular thalamus had dense rabies-labelled inputs to BLA VGLUT2+ neurons.

Fig. 2B-C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

ENTl (Entorhinal area, lateral part) MBA:918 synapses onto BLA glutamatergic principal neurons nt-wprma5fcrr · Mouse

Lateral entorhinal cortex contained dense presynaptic cells labelled from BLA VGLUT2+ starters.

Fig. 2B-C

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TH (Thalamus) MBA:549 synapses onto BLA glutamatergic principal neurons nt-wprma5fcrr · Mouse

Thalamic neurons were labelled as monosynaptic inputs to BLA VGLUT2+ neurons.

Fig. 6C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

SI (Substantia innominata) MBA:342 synapses onto CEAl somatostatin-expressing neurons nt-t6ymz01hv4 · Mouse

Substantia innominata was a dense, novel input to CeA SST+ neurons, about 1.97% of inputs.

Fig. 5B-C; Results, Comparison of Inputs

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

PIR (Piriform area) MBA:961 synapses onto BLA parvalbumin-expressing interneurons nt-fwck8mp6aj · Mouse

Piriform cortex densely labelled as input to BLA PV+ neurons, sending more input to PV+ than to VGLUT2+ BLA cells.

Fig. 3B-C; Fig. 6A

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

OLF (Olfactory areas) MBA:698 synapses onto CEAl PKC-delta-expressing neurons nt-g513b58b0y · Mouse

Olfactory areas contributed a small share of inputs to CeA PKC-δ+ neurons.

Fig. 6D

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

MRN (Midbrain reticular nucleus) MBA:128 synapses onto CEAl somatostatin-expressing neurons nt-t6ymz01hv4 · Mouse

Deep mesencephalic nucleus provided about 2.55% of inputs to CeA SST+ neurons, described as novel.

Results, Comparison of Inputs

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

ORBm (Orbital area, medial part) MBA:731 synapses onto BLA parvalbumin-expressing interneurons nt-fwck8mp6aj · Mouse

Medial orbital cortex showed dense rabies-labelled input cells to BLA PV+ neurons.

Fig. 3B-C

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HY (Hypothalamus) MBA:1097 synapses onto CEAl PKC-delta-expressing neurons nt-g513b58b0y · Mouse

Hypothalamus was the second largest input area for CeA PKC-δ+ neurons.

Fig. 6D

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

PVT (Paraventricular nucleus of the thalamus) MBA:149 synapses onto CEAl somatostatin-expressing neurons nt-t6ymz01hv4 · Mouse

Paraventricular thalamus contained dense inputs to CeA SST+ neurons.

Fig. 5B-C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

STR (Striatum) MBA:477 synapses onto CEAl PKC-delta-expressing neurons nt-g513b58b0y · Mouse

Striatum was the largest source of inputs to CeA PKC-δ+ neurons, more than to SST+ neurons.

Fig. 6D

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

VMH (Ventromedial hypothalamic nucleus) MBA:693 synapses onto CEAl PKC-delta-expressing neurons nt-g513b58b0y · Mouse

Ventromedial hypothalamus contained dense rabies-labelled inputs to CeA PKC-δ+ neurons.

Fig. 4B-C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

SI (Substantia innominata) MBA:342 synapses onto CEAl PKC-delta-expressing neurons nt-g513b58b0y · Mouse

Substantia innominata was identified as a novel input to CeA PKC-δ+ neurons, about 1.93% of inputs.

Results, Comparison of Inputs

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

AUD (Auditory areas) MBA:247 synapses onto CEAl somatostatin-expressing neurons nt-t6ymz01hv4 · Mouse

Auditory cortex gave dense monosynaptic inputs to CeA SST+ neurons.

Fig. 5B-C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

AI (Agranular insular area) MBA:95 synapses onto BLA glutamatergic principal neurons nt-wprma5fcrr · Mouse

Agranular insular cortex showed dense rabies-labelled inputs to BLA VGLUT2+ neurons.

Fig. 2B-C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

PIR (Piriform area) MBA:961 synapses onto BLA glutamatergic principal neurons nt-wprma5fcrr · Mouse

Dense rabies-labelled input cells were seen in piriform cortex after tracing from BLA VGLUT2+ neurons.

Fig. 2B-C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

Isocortex MBA:315 synapses onto BLA parvalbumin-expressing interneurons nt-fwck8mp6aj · Mouse

Isocortex provided the second largest share of inputs to BLA PV+ neurons.

Fig. 6C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

OLF (Olfactory areas) MBA:698 synapses onto BLA glutamatergic principal neurons nt-wprma5fcrr · Mouse

Olfactory areas contained a share of input neurons to BLA VGLUT2+ cells, smaller than their share to PV+ cells.

Fig. 6C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

PERI (Perirhinal area) MBA:922 synapses onto BLA parvalbumin-expressing interneurons nt-fwck8mp6aj · Mouse

Perirhinal cortex contained dense presynaptic cells to BLA PV+ neurons.

Fig. 3B-C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

HPF (Hippocampal formation) MBA:1089 synapses onto CEAl PKC-delta-expressing neurons nt-g513b58b0y · Mouse

Hippocampal formation gave the smallest share of inputs to CeA PKC-δ+ neurons.

Fig. 6D

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

HPF (Hippocampal formation) MBA:1089 synapses onto BLA glutamatergic principal neurons nt-wprma5fcrr · Mouse

Hippocampal formation provided a substantial fraction of rabies-labelled inputs to BLA VGLUT2+ neurons.

Fig. 6C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

Isocortex MBA:315 synapses onto CEAl somatostatin-expressing neurons nt-t6ymz01hv4 · Mouse

Isocortex was the largest input area for CeA SST+ neurons, larger than for PKC-δ+ neurons.

Fig. 6D

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

MRN (Midbrain reticular nucleus) MBA:128 synapses onto CEAl PKC-delta-expressing neurons nt-g513b58b0y · Mouse

Deep mesencephalic nucleus was a novel input source to CeA PKC-δ+ neurons, about 2.51% of inputs.

Results, Comparison of Inputs

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

PO (Posterior complex of the thalamus) MBA:1020 synapses onto CEAl PKC-delta-expressing neurons nt-g513b58b0y · Mouse

Posterior thalamic group showed dense input cells to CeA PKC-δ+ neurons.

Fig. 4B-C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

STR (Striatum) MBA:477 synapses onto CEAl somatostatin-expressing neurons nt-t6ymz01hv4 · Mouse

Striatum gave the smallest share of inputs to CeA SST+ neurons, far less than to PKC-δ+ neurons.

Fig. 6D

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

ZI (Zona incerta) MBA:797 synapses onto CEAl PKC-delta-expressing neurons nt-g513b58b0y · Mouse

Zona incerta was a novel, minor input to CeA PKC-δ+ neurons, about 0.8% of inputs.

Results, Comparison of Inputs

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

CA1 (Field CA1) MBA:382 synapses onto CEAl somatostatin-expressing neurons nt-t6ymz01hv4 · Mouse

CA1 densely labelled as input to CeA SST+ neurons, with more input to SST+ than to PKC-δ+ cells.

Fig. 5B-C; Fig. 6B

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

PSTN (Parasubthalamic nucleus) MBA:364 synapses onto CEAl somatostatin-expressing neurons nt-t6ymz01hv4 · Mouse

Parasubthalamic nucleus contained dense presynaptic cells to CeA SST+ neurons.

Fig. 5B-C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

PVT (Paraventricular nucleus of the thalamus) MBA:149 synapses onto BLA parvalbumin-expressing interneurons nt-fwck8mp6aj · Mouse

Paraventricular thalamus densely labelled as input to BLA PV+ neurons.

Fig. 3B-C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

TU (Tuberal nucleus) MBA:614 synapses onto CEAl PKC-delta-expressing neurons nt-g513b58b0y · Mouse

Tuber cinereum area contributed about 3.09% of monosynaptic inputs to CeA PKC-δ+ neurons.

Results, Comparison of Inputs

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

AI (Agranular insular area) MBA:95 synapses onto CEAl somatostatin-expressing neurons nt-t6ymz01hv4 · Mouse

Agranular insular cortex contained dense presynaptic cells to CeA SST+ neurons.

Fig. 5B-C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

OLF (Olfactory areas) MBA:698 synapses onto BLA parvalbumin-expressing interneurons nt-fwck8mp6aj · Mouse

Olfactory areas were the largest source of monosynaptic input to BLA PV+ neurons.

Fig. 6C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

MB (Midbrain) MBA:313 synapses onto BLA glutamatergic principal neurons nt-wprma5fcrr · Mouse

A small fraction of input neurons to BLA VGLUT2+ cells were in the midbrain.

Fig. 6C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

BST (Bed nuclei of the stria terminalis) MBA:351 synapses onto CEAl somatostatin-expressing neurons nt-t6ymz01hv4 · Mouse

Bed nucleus of the stria terminalis densely labelled as input to CeA SST+ neurons.

Fig. 5B-C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

ENTl (Entorhinal area, lateral part) MBA:918 synapses onto BLA parvalbumin-expressing interneurons nt-fwck8mp6aj · Mouse

Dense rabies-labelled inputs to BLA PV+ neurons arose in lateral entorhinal cortex.

Fig. 3B-C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

TH (Thalamus) MBA:549 synapses onto CEAl somatostatin-expressing neurons nt-t6ymz01hv4 · Mouse

Thalamus contained a substantial share of input neurons to CeA SST+ cells.

Fig. 6D

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

PAL (Pallidum) MBA:803 synapses onto CEAl somatostatin-expressing neurons nt-t6ymz01hv4 · Mouse

Pallidum provided rabies-labelled inputs to CeA SST+ neurons.

Fig. 6D

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

PAL (Pallidum) MBA:803 synapses onto BLA glutamatergic principal neurons nt-wprma5fcrr · Mouse

Pallidal neurons provided rabies-labelled input to BLA VGLUT2+ neurons.

Fig. 6C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

ACB (Nucleus accumbens) MBA:56 synapses onto CEAl PKC-delta-expressing neurons nt-g513b58b0y · Mouse

Nucleus accumbens contained dense presynaptic cells to CeA PKC-δ+ neurons.

Fig. 4B-C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

MB (Midbrain) MBA:313 synapses onto CEAl somatostatin-expressing neurons nt-t6ymz01hv4 · Mouse

Midbrain provided a small share of inputs to CeA SST+ neurons.

Fig. 6D

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

CP (Caudoputamen) MBA:672 synapses onto BLA parvalbumin-expressing interneurons nt-fwck8mp6aj · Mouse

Caudate-putamen contained dense inputs to BLA PV+ neurons, though fewer proportionally than to VGLUT2+ neurons.

Fig. 3B-C; Fig. 6A

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

TEa (Temporal association areas) MBA:541 synapses onto CEAl somatostatin-expressing neurons nt-t6ymz01hv4 · Mouse

Temporal association cortex densely labelled as input to CeA SST+ neurons, more than to PKC-δ+ neurons.

Fig. 5B-C; Fig. 6B

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

AI (Agranular insular area) MBA:95 synapses onto BLA parvalbumin-expressing interneurons nt-fwck8mp6aj · Mouse

Agranular insular cortex gave dense monosynaptic input to BLA PV+ neurons.

Fig. 3B-C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

CA1 (Field CA1) MBA:382 synapses onto BLA parvalbumin-expressing interneurons nt-fwck8mp6aj · Mouse

CA1 contained dense rabies-labelled input cells to BLA PV+ neurons.

Fig. 3B-C; Fig. 6A

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

TH (Thalamus) MBA:549 synapses onto BLA parvalbumin-expressing interneurons nt-fwck8mp6aj · Mouse

Thalamus contained input neurons to BLA PV+ cells.

Fig. 6C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

SI (Substantia innominata) MBA:342 synapses onto BLA parvalbumin-expressing interneurons nt-fwck8mp6aj · Mouse

Substantia innominata was a dense, novel input source to BLA PV+ neurons, about 4.58% of inputs.

Fig. 3B-C; Results, Comparison of Inputs

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

HPF (Hippocampal formation) MBA:1089 synapses onto BLA parvalbumin-expressing interneurons nt-fwck8mp6aj · Mouse

Hippocampal formation neurons were labelled as inputs to BLA PV+ neurons.

Fig. 6C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.