GPR17 modulates anxiety-like behaviors via basolateral amygdala to ventral hippocampal CA1 glutamatergic projection

BLA glutamatergic principal neurons nt-wprma5fcrr functionally connects to CA1 (Field CA1) MBA:382 · Mouse

After ChR2 expression in BLA CaMKIIα neurons, blue light applied to BLA terminals evoked inward excitatory postsynaptic currents in EGFP-labelled vCA1 pyramidal neurons held at −70 mV; the amplitude was larger in stressed mice and reduced by intra-BLA cangrelor.

Fig. 8H–J

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

BLA (Basolateral amygdalar nucleus) MBA:295 projects to ILA (Infralimbic area) MBA:44 · Mouse

Anterograde labelling from BLA with AAV-CaMKIIα-mCherry revealed fibres in the infralimbic cortex.

Fig. 8A–C, Fig. S5A

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

BLA (Basolateral amygdalar nucleus) MBA:295 projects to CA1 (Field CA1) MBA:382 · Mouse

AAV-CaMKIIα-mCherry injected into BLA labelled axon terminals in ventral hippocampal CA1, showing that BLA glutamatergic neurons send axons to vCA1.

Fig. 8A–C

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

BLA (Basolateral amygdalar nucleus) MBA:295 projects to BST (Bed nuclei of the stria terminalis) MBA:351 · Mouse

Anterograde tracing from BLA labelled projections reaching the bed nucleus of the stria terminalis.

Fig. 8A–C, Fig. S5A

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

BLA (Basolateral amygdalar nucleus) MBA:295 projects to PL (Prelimbic area) MBA:972 · Mouse

mCherry-labelled axons from BLA CaMKIIα neurons were found in prelimbic cortex.

Fig. 8A–C, Fig. S5A

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

BLA (Basolateral amygdalar nucleus) MBA:295 projects to HPF (Hippocampal formation) MBA:1089 · Mouse

Anterograde viral labelling of BLA glutamatergic neurons showed terminal fields in both dorsal and ventral hippocampus.

Fig. 8A–C, Fig. S5A

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

BLA (Basolateral amygdalar nucleus) MBA:295 projects to LS (Lateral septal nucleus) MBA:242 · Mouse

BLA glutamatergic neurons labelled with AAV-CaMKIIα-mCherry sent axons to the lateral septal nucleus.

Fig. 8A–C, Fig. S5A

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.