Prepronociceptin-Expressing Neurons in the Extended Amygdala Encode and Promote Rapid Arousal Responses to Motivationally Salient Stimuli

BST (Bed nuclei of the stria terminalis) MBA:351 projects to PB (Parabrachial nucleus) MBA:867 · Mouse

Fiber-density quantification showed only sparse to nearly absent labelling of Pnoc BNST axons in the parabrachial nucleus.

Fig. 5D; Results

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

BST (Bed nuclei of the stria terminalis) MBA:351 projects to PAG (Periaqueductal gray) MBA:795 · Mouse

Among adBNST output regions examined, the periaqueductal gray contained only sparse to nearly absent fibers from labelled Pnoc BNST neurons.

Fig. 5D; Results

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

BST (Bed nuclei of the stria terminalis) MBA:351 projects to MEA (Medial amygdalar nucleus) MBA:403 · Mouse

Fluorescent labelling of Pnoc neurons and their axons in adBNST produced prominent distal fiber labelling in the medial amygdala (notably its posterodorsal portion), quantified as fiber density across target regions in six mice.

Fig. 5D–5E

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

BST (Bed nuclei of the stria terminalis) MBA:351 projects to MPO (Medial preoptic area) MBA:523 · Mouse

Axonal labelling from virally tagged Pnoc neurons in adBNST was prominent in the medial preoptic area, one of the two main distal targets identified by fiber-density quantification.

Fig. 5D–5E

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

BST (Bed nuclei of the stria terminalis) MBA:351 projects to VMH (Ventromedial hypothalamic nucleus) MBA:693 · Mouse

Only sparse to nearly absent axonal labelling from Pnoc BNST neurons was quantified in the ventromedial hypothalamus.

Fig. 5D; Results

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

BST (Bed nuclei of the stria terminalis) MBA:351 projects to LHA (Lateral hypothalamic area) MBA:194 · Mouse

Fiber-density measurements revealed only sparse to nearly absent labelling from Pnoc BNST axons in the lateral hypothalamic area.

Fig. 5D; Results

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

BST (Bed nuclei of the stria terminalis) MBA:351 projects to ARH (Arcuate hypothalamic nucleus) MBA:223 · Mouse

Quantification of fiber density in adBNST output regions showed only sparse to nearly undetectable axonal labelling from Pnoc BNST neurons in the arcuate nucleus.

Fig. 5D; Results

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.