Coactivation of thalamic and cortical pathways induces input timing–dependent plasticity in amygdala

CTX (Cerebral cortex) UBERON:0000956 functionally connects to Rat lateral amygdaloid nucleus principal neurons nt-gypnv5m278 · Rat

Stimulating cortical afferents in the external capsule evoked glutamatergic EPSCs in lateral amygdala principal neurons in rat slices. These EPSCs had AMPA and kainate receptor components that were blocked by NBQX, and they were potentiated after pairing with prior thalamic stimulation.

Fig. 1a,c,e; Fig. 5a,b; Fig. 6a,b; Supplementary Fig. 1

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TH (Thalamus) UBERON:0001897 functionally connects to Rat lateral amygdaloid nucleus principal neurons nt-gypnv5m278 · Rat

In rat slices, stimulating thalamic afferents in the internal capsule evoked EPSCs in lateral amygdala principal neurons. The EPSCs were recorded with GABA-A receptors blocked and were mediated by AMPA and kainate receptors, being abolished by NBQX.

Fig. 1a,d,f; Fig. 5a,b; Supplementary Fig. 1

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