Basal forebrain cholinergic signaling in the basolateral amygdala promotes strength and durability of fear memories

SI (Substantia innominata) UBERON:0003017 projects to HPF (Hippocampal formation) UBERON:0002421 · Rat

No eYFP-positive terminals from virally labelled NBM cholinergic neurons were detected in dorsal hippocampus.

Fig. 1D, E

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

NDB (Diagonal band nucleus) UBERON:0001879 projects to BLN (basolateral amygdaloid nuclear complex) UBERON:0006107 · Rat

Retrograde Cre-dependent virus injected in the BLA labelled cholinergic neurons in the HDB.

Fig. 1M, N, Q, R

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

NDB (Diagonal band nucleus) UBERON:0001879 projects to BLN (basolateral amygdaloid nuclear complex) UBERON:0006107 · Rat

Cre-dependent viral labelling of HDB cholinergic neurons produced eYFP-positive terminals in the basolateral amygdala.

Fig. 1G–L

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

NDB (Diagonal band nucleus) UBERON:0001879 projects to ILA (Infralimbic area) UBERON:8440033 · Rat

Virally labelled HDB cholinergic neurons produced eYFP-positive terminals in infralimbic cortex.

Fig. 1J–L

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

SI (Substantia innominata) UBERON:0003017 projects to PL (Prelimbic area) UBERON:8440032 · Rat

After Cre-dependent viral labelling of NBM cholinergic neurons, no eYFP-positive terminals were seen in prelimbic cortex.

Fig. 1D, E

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

MS (Medial septal nucleus) UBERON:0001877 projects to BLN (basolateral amygdaloid nuclear complex) UBERON:0006107 · Rat

Retrograde labelling from the BLA revealed cholinergic cells in the HDB but not in the neighbouring medial septum or vertical limb of the diagonal band.

Fig. S1E

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

SI (Substantia innominata) UBERON:0003017 projects to ILA (Infralimbic area) UBERON:8440033 · Rat

Labelled NBM cholinergic neurons did not give rise to eYFP-positive terminals in infralimbic cortex.

Fig. 1D, E

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

SI (Substantia innominata) UBERON:0003017 projects to BLN (basolateral amygdaloid nuclear complex) UBERON:0006107 · Rat

A retrograde-serotype Cre-dependent eNpHR3.0-eYFP virus infused into the BLA of ChAT::Cre rats labelled eYFP-positive cell bodies in the NBM that were choline acetyltransferase positive.

Fig. 1M–P

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

MS (Medial septal nucleus) UBERON:0001877 projects to BLN (basolateral amygdaloid nuclear complex) UBERON:0006107 · Rat

Infusing the Cre-dependent eNpHR3.0-eYFP virus into the medial septum produced no eYFP-positive terminals in the BLA.

Fig. S1F–M

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

NDB (Diagonal band nucleus) UBERON:0001879 projects to HPF (Hippocampal formation) UBERON:0002421 · Rat

eYFP-positive terminals from labelled HDB cholinergic neurons were found in dorsal hippocampus.

Fig. 1J–L

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

SI (Substantia innominata) UBERON:0003017 projects to BLN (basolateral amygdaloid nuclear complex) UBERON:0006107 · Rat

Cre-dependent eNpHR3.0-eYFP virus infused into the NBM of ChAT::Cre rats labelled only cholinergic cells and produced eYFP-positive axon terminals in the basolateral amygdala.

Fig. 1A–F; Results, 'NBM and HDB cholinergic neurons project to the BLA'

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

NDB (Diagonal band nucleus) UBERON:0001879 projects to PL (Prelimbic area) UBERON:8440032 · Rat

HDB cholinergic neurons labelled with the Cre-dependent virus sent eYFP-positive terminals to prelimbic cortex.

Fig. 1J–L

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.