DREADD-Induced Silencing of the Medial Olfactory Tubercle Disrupts the Preference of Female Mice for Opposite-Sex Chemosignals

OT (Olfactory tubercle) MBA:754 projects to CP (Caudoputamen) MBA:672 · Mouse

The caudate putamen showed sparse mCitrine-positive fiber labeling after AAV infection of the mOT.

Results, Localization of hM4Di infection

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

OT (Olfactory tubercle) MBA:754 projects to VTA (Ventral tegmental area) MBA:749 · Mouse

Sparse mCitrine-labeled fibers from the infected mOT were seen in the ventral tegmental area.

Results, Localization of hM4Di infection

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

OT (Olfactory tubercle) MBA:754 projects to PIR (Piriform area) MBA:961 · Mouse

Labeled fibers from the mOT infection were found in both anterior and posterior piriform cortex. A small number of infected cell bodies were also present in piriform cortex.

Results, Localization of hM4Di infection

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

OT (Olfactory tubercle) MBA:754 projects to MOB (Main olfactory bulb) MBA:507 · Mouse

After AAV-hM4Di-mCitrine was expressed in the mOT, mCitrine-labeled fibers were found in the main olfactory bulb.

Results, Localization of hM4Di infection

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

OT (Olfactory tubercle) MBA:754 projects to COApl (Cortical amygdalar area, posterior part, lateral zone) MBA:655 · Mouse

After mOT infection with the AAV, mCitrine-positive fibers were seen in the posterolateral cortical amygdala.

Results, Localization of hM4Di infection

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

MEA (Medial amygdalar nucleus) MBA:403 projects to OT (Olfactory tubercle) MBA:754 · Mouse

After cholera toxin B was injected into the medial olfactory tubercle of female mice, retrogradely labeled cell bodies appeared in the anterior medial amygdala. A subset of these cells also expressed Fos after exposure to male odors.

Results, Experiment 1; Fig. 3C; Fig. 4A,C,I

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

OT (Olfactory tubercle) MBA:754 projects to AON (Anterior olfactory nucleus) MBA:159 · Mouse

Viral mCitrine expression in the mOT revealed labeled fibers in the anterior olfactory nucleus.

Results, Localization of hM4Di infection

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

VTA (Ventral tegmental area) MBA:749 projects to OT (Olfactory tubercle) MBA:754 · Mouse

Injecting CTb into the mOT retrogradely labeled VTA neurons. Some of these mOT-projecting VTA cells became Fos-positive when the mice were exposed to male bedding volatiles.

Results, Experiment 1; Fig. 3C; Fig. 4B,F,I

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

OT (Olfactory tubercle) MBA:754 projects to PALv (Pallidum, ventral region) MBA:835 · Mouse

After the mOT was infected with the AAV, mCitrine-labeled fibers appeared in the ventral pallidum.

Results, Localization of hM4Di infection

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.