Neuronal Subtypes and Connectivity of the Adult Mouse Paralaminar Amygdala

NLOT (Nucleus of the lateral olfactory tract) MBA:619 projects to CTXsp (Cortical subplate) MBA:703 · Mouse

Anterograde tracer injected into the nLOT labelled fibres in the PL, and these carried VGlut2-positive puncta.

Fig. 4B

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

CTXsp (Cortical subplate) MBA:703 projects to AI (Agranular insular area) MBA:95 · Mouse

PL output terminals labelled the agranular insular cortex, one of the input regions with strong signal.

Fig. 5B, Fig. 7

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

PIR (Piriform area) MBA:961 projects to CTXsp (Cortical subplate) MBA:703 · Mouse

Retrograde virus injected into the PL labelled neurons in the piriform cortex.

Fig. 3B

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

CTXsp (Cortical subplate) MBA:703 projects to DG (Dentate gyrus) MBA:726 · Mouse

The dentate gyrus showed PL-derived synaptic terminal labelling.

Fig. 5B, Fig. 8

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

COA (Cortical amygdalar area) MBA:631 projects to CTXsp (Cortical subplate) MBA:703 · Mouse

Anterograde tracer injected into the cortical amygdala labelled fibres in the PL, and these carried VGlut2-positive puncta.

Fig. 4B

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

AI (Agranular insular area) MBA:95 projects to CTXsp (Cortical subplate) MBA:703 · Mouse

PL retrograde injections labelled input neurons in the agranular insular cortex, which held over 1% of all labelled cells.

Fig. 3B,C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

BLA (Basolateral amygdalar nucleus) MBA:295 projects to CTXsp (Cortical subplate) MBA:703 · Mouse

An AAV5-mCherry injection into the basolateral complex produced labelled fibres in the PL, with puncta colocalizing with VGlut2.

Fig. 4B

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

CTXsp (Cortical subplate) MBA:703 projects to MOB (Main olfactory bulb) MBA:507 · Mouse

Syp-EGFP terminals from PL neurons were observed in the main olfactory bulb.

Fig. 5B, Fig. 7

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

CTXsp (Cortical subplate) MBA:703 projects to BLA (Basolateral amygdalar nucleus) MBA:295 · Mouse

Dense Syp-EGFP terminals from VGlut1 PL neurons were seen in the basolateral amygdala.

Fig. 5B, Fig. 6

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

CTXsp (Cortical subplate) MBA:703 projects to CP (Caudoputamen) MBA:672 · Mouse

The caudate and putamen showed no PL terminal labelling.

Results, PL outputs section

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

AON (Anterior olfactory nucleus) MBA:159 projects to CTXsp (Cortical subplate) MBA:703 · Mouse

After AAV2-retro injection into the PL, tdTomato-labelled input neurons appeared in the anterior olfactory nucleus.

Fig. 3B

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

CTXsp (Cortical subplate) MBA:703 projects to TH (Thalamus) MBA:549 · Mouse

The brain-wide survey found no PL terminal labelling in the thalamus.

Results, PL outputs section

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

CTXsp (Cortical subplate) MBA:703 projects to NLOT (Nucleus of the lateral olfactory tract) MBA:619 · Mouse

Cre-dependent Syp-EGFP labelling of VGlut1 PL neurons gave the strongest terminal signal of any region in the nLOT.

Fig. 5B, Fig. 6

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

CTXsp (Cortical subplate) MBA:703 projects to AON (Anterior olfactory nucleus) MBA:159 · Mouse

PL output terminals labelled the anterior olfactory nucleus, one of the input regions with strong signal.

Fig. 5B, Fig. 7

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

CTXsp (Cortical subplate) MBA:703 projects to COAa (Cortical amygdalar area, anterior part) MBA:639 · Mouse

PL terminals were dense in the cortical amygdala and densest in its anterior subregion.

Fig. 5B, Fig. 6

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

ENT (Entorhinal area) MBA:909 projects to CTXsp (Cortical subplate) MBA:703 · Mouse

Anterograde tracer injected into the entorhinal cortex labelled fibres in the PL, and these carried VGlut2-positive puncta.

Fig. 4B

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

BLA (Basolateral amygdalar nucleus) MBA:295 projects to CTXsp (Cortical subplate) MBA:703 · Mouse

PL retrograde injections labelled input neurons in the amygdala basolateral complex, which held over 1% of all labelled cells.

Fig. 3B,C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

COA (Cortical amygdalar area) MBA:631 projects to CTXsp (Cortical subplate) MBA:703 · Mouse

PL retrograde injections labelled input neurons in the cortical amygdala, which held over 1% of all labelled cells.

Fig. 3B,C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

CTXsp (Cortical subplate) MBA:703 projects to MB (Midbrain) MBA:313 · Mouse

PL fibres extended into the brainstem, and putative terminals were present in the substantia nigra.

Fig. 5B, Fig. 8

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

CTXsp (Cortical subplate) MBA:703 projects to MY (Medulla) MBA:354 · Mouse

The medulla showed no PL terminal labelling.

Results, PL outputs section

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

OT (Olfactory tubercle) MBA:754 projects to CTXsp (Cortical subplate) MBA:703 · Mouse

Retrograde virus injected into the PL labelled neurons in the olfactory tubercle.

Fig. 3B

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

CTXsp (Cortical subplate) MBA:703 projects to MEZ (Hypothalamic medial zone) MBA:467 · Mouse

Putative PL synaptic terminals were present in the medial hypothalamus.

Fig. 5B, Fig. 8

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

ENT (Entorhinal area) MBA:909 projects to CTXsp (Cortical subplate) MBA:703 · Mouse

PL retrograde injections labelled input neurons in the entorhinal cortex, which held over 1% of all labelled cells.

Fig. 3B,C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

CTXsp (Cortical subplate) MBA:703 projects to AOB (Accessory olfactory bulb) MBA:151 · Mouse

Syp-EGFP terminals from PL neurons were observed in the accessory olfactory bulb.

Fig. 5B, Fig. 7

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

NLOT (Nucleus of the lateral olfactory tract) MBA:619 projects to CTXsp (Cortical subplate) MBA:703 · Mouse

PL retrograde injections labelled input neurons in the nucleus of the lateral olfactory tract, which held over 1% of all labelled cells.

Fig. 3B,C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

CTXsp (Cortical subplate) MBA:703 projects to ACB (Nucleus accumbens) MBA:56 · Mouse

The nucleus accumbens showed PL-derived synaptic terminal labelling.

Fig. 5B, Fig. 8

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

CTXsp (Cortical subplate) MBA:703 projects to SUB (Subiculum) MBA:502 · Mouse

The subiculum showed PL-derived synaptic terminal labelling.

Fig. 5B, Fig. 8

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

CTXsp (Cortical subplate) MBA:703 projects to OT (Olfactory tubercle) MBA:754 · Mouse

PL output terminals labelled the olfactory tubercle, one of the input regions with strong signal.

Fig. 5B, Fig. 7

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

CTXsp (Cortical subplate) MBA:703 projects to PB (Parabrachial nucleus) MBA:867 · Mouse

Putative PL synaptic terminals were present in the parabrachial nucleus.

Fig. 5B, Fig. 8

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

CTXsp (Cortical subplate) MBA:703 projects to LHA (Lateral hypothalamic area) MBA:194 · Mouse

PL fibres reached the hypothalamus and left putative synaptic terminals in the lateral hypothalamus.

Fig. 5B, Fig. 8

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

AI (Agranular insular area) MBA:95 projects to CTXsp (Cortical subplate) MBA:703 · Mouse

Anterograde tracer injected into the agranular insular cortex labelled fibres in the PL, and these carried VGlut2-positive puncta.

Fig. 4B

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

CTXsp (Cortical subplate) MBA:703 projects to ENT (Entorhinal area) MBA:909 · Mouse

The entorhinal cortex, an input region, showed strong reciprocal Syp-EGFP terminal labelling from the PL.

Fig. 5B, Fig. 7

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

CTXsp (Cortical subplate) MBA:703 projects to PIR (Piriform area) MBA:961 · Mouse

PL synaptic terminals, with EGFP colocalized on tdTomato fibres, were found in the piriform cortex, one of the input regions that showed strong signal.

Fig. 5B, Fig. 7

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.