Generation and Characterization of a NovelPrkcd-Cre Rat Model

CEA (central amygdaloid nucleus) UBERON:0002883 projects to PPN (Pedunculopontine nucleus) UBERON:0002142 · Rat

CeA PKCδ+ axons labelled the mesopontine tegmentum, including the pedunculopontine tegmental subnucleus (and the microcellular tegmental nucleus).

Fig. 4F; Results, Anterograde tracing of CeA PKCδ+ neurons

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

CEA (central amygdaloid nucleus) UBERON:0002883 projects to SNc (Substantia nigra, compact part) UBERON:0001965 · Rat

Labelled axons of CeA PKCδ+ neurons reached the substantia nigra pars compacta.

Fig. 4E; Results, Anterograde tracing of CeA PKCδ+ neurons

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

CEA (central amygdaloid nucleus) UBERON:0002883 projects to AI (Agranular insular area) UBERON:0034893 · Rat

Cre-dependent mCherry expressed in CeA PKCδ+ cells of Prkcd-Cre rats labelled axon terminals in the insular cortex.

Fig. 4B; Results, Anterograde tracing of CeA PKCδ+ neurons

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

CEA (central amygdaloid nucleus) UBERON:0002883 projects to VTA (Ventral tegmental area) UBERON:0002691 · Rat

mCherry-labelled terminals from CeA PKCδ+ neurons were present in the ventral tegmental area.

Fig. 4E; Results, Anterograde tracing of CeA PKCδ+ neurons

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

CEA (central amygdaloid nucleus) UBERON:0002883 projects to ZI (Zona incerta) UBERON:0001907 · Rat

mCherry-labelled fibres of CeA PKCδ+ neurons innervated the zona incerta.

Fig. 4D; Results, Anterograde tracing of CeA PKCδ+ neurons

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

CEA (central amygdaloid nucleus) UBERON:0002883 projects to BLA (basal amygdaloid nucleus) UBERON:0002887 · Rat

Anterograde tracing showed labelled CeA PKCδ+ axons in the basolateral amygdala.

Fig. 4D; Results, Anterograde tracing of CeA PKCδ+ neurons

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

CEA (central amygdaloid nucleus) UBERON:0002883 functionally connects to PAG (Periaqueductal gray) UBERON:0003040 · Rat

Photostimulation of ChR2-expressing CeA PKCδ+ fibres in the ventrolateral PAG evoked IPSCs (mean ~58 pA) in only a minority of recorded vlPAG neurons, which the authors describe as weak connectivity.

Fig. 6G,H

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

CEA (central amygdaloid nucleus) UBERON:0002883 projects to MPO (Medial preoptic area) UBERON:0007769 · Rat

Among hypothalamic targets, labelled terminals of CeA PKCδ+ neurons were particularly evident in the medial preoptic area.

Fig. 4C; Results, Anterograde tracing of CeA PKCδ+ neurons

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

CEA (central amygdaloid nucleus) UBERON:0002883 projects to PALv (Pallidum, ventral region) UBERON:0002778 · Rat

Labelled terminals from CeA PKCδ+ neurons were found in the ventral pallidum.

Fig. 4D; Results, Anterograde tracing of CeA PKCδ+ neurons

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

CEA (central amygdaloid nucleus) UBERON:0002883 projects to SEP (septal nuclei) UBERON:0002663 · Rat

mCherry-positive axons from CeA PKCδ+ cells were detected in the septal nuclei.

Fig. 4C; Results, Anterograde tracing of CeA PKCδ+ neurons

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

CEA (central amygdaloid nucleus) UBERON:0002883 projects to COA (cortical amygdaloid nucleus) UBERON:0002891 · Rat

Fibres originating from CeA PKCδ+ neurons targeted several nuclei of the periamygdaloid cortex.

Fig. 4; Results, Anterograde tracing of CeA PKCδ+ neurons

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

CEA (central amygdaloid nucleus) UBERON:0002883 projects to HY (Hypothalamus) UBERON:0001898 · Rat

Viral anterograde tracing from CeA PKCδ+ neurons labelled several hypothalamic nuclei.

Fig. 4C; Results, Anterograde tracing of CeA PKCδ+ neurons

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

CEA (central amygdaloid nucleus) UBERON:0002883 projects to PVT (Paraventricular nucleus of the thalamus) UBERON:0001920 · Rat

Anterograde tracing from rat CeA PKCδ+ neurons labelled the paraventricular nucleus of the thalamus.

Fig. 4D; Results, Anterograde tracing of CeA PKCδ+ neurons

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

CEA (central amygdaloid nucleus) UBERON:0002883 projects to BST (Bed nuclei of the stria terminalis) UBERON:0001880 · Rat

mCherry-labelled fibres from CeA PKCδ+ neurons were seen in the bed nucleus of the stria terminalis.

Fig. 4C; Results, Anterograde tracing of CeA PKCδ+ neurons

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

CEA (central amygdaloid nucleus) UBERON:0002883 projects to PAG (Periaqueductal gray) UBERON:0003040 · Rat

The authors report pronounced mCherry-labelled projections from CeA PKCδ+ neurons to the ventrolateral column of the periaqueductal gray.

Fig. 4F; Results, Anterograde tracing of CeA PKCδ+ neurons

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.