Posterodorsal Medial Amygdala Regulation of Female Social Behavior: GABA versus Glutamate Projections

MEA GABAergic neurons nt-bqdbjsy396 projects to VMH (Ventromedial hypothalamic nucleus) MBA:693 · Mouse

Labelled fibers from MeApd GABAergic neurons were seen in the ventrolateral VMH and across the other VMH subdivisions.

Fig. 3B; Results, AAV expression and fiber optic cannula placement

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

MEA GABAergic neurons nt-bqdbjsy396 projects to ARH (Arcuate hypothalamic nucleus) MBA:223 · Mouse

No virally labelled fibers from MeApd GABAergic neurons were found in the arcuate nucleus.

Fig. 3C; Results, AAV expression and fiber optic cannula placement

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

MEA GABAergic neurons nt-bqdbjsy396 functionally connects to MPN (Medial preoptic nucleus) MBA:515 · Mouse

Photoinhibiting MeApd GABAergic neurons did not change c-Fos cell counts in the medial MPN compared with controls.

Results, Optogenetic inhibition of VGAT neurons in the MeApd decreased c-Fos expression

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

MEA GABAergic neurons nt-bqdbjsy396 functionally connects to VMH (Ventromedial hypothalamic nucleus) MBA:693 · Mouse

Halorhodopsin silencing of MeApd VGAT neurons during mating lowered the number of c-Fos-positive cells in the VMHvl relative to control-virus mice.

Fig. 6

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

MEA glutamatergic neurons nt-3kvfdzf7wn projects to VMH (Ventromedial hypothalamic nucleus) MBA:693 · Mouse

Glutamatergic MeApd fibers were observed in the VMH, including the ventrolateral part, which received less of them than the rest of the nucleus.

Fig. 3E; Results, AAV expression and fiber optic cannula placement

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

MEA GABAergic neurons nt-bqdbjsy396 projects to MPN (Medial preoptic nucleus) MBA:515 · Mouse

Cre-dependent eNpHR-EYFP expressed in MeApd VGAT neurons labelled fibers innervating the medial preoptic nucleus, spread roughly evenly across its subdivisions.

Fig. 3A; Results, AAV expression and fiber optic cannula placement

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

MEA GABAergic neurons nt-bqdbjsy396 functionally connects to ARH (Arcuate hypothalamic nucleus) MBA:223 · Mouse

Silencing MeApd VGAT neurons left arcuate c-Fos counts unchanged.

Results, Optogenetic inhibition of VGAT neurons in the MeApd decreased c-Fos expression

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

MEA glutamatergic neurons nt-3kvfdzf7wn functionally connects to MPN (Medial preoptic nucleus) MBA:515 · Mouse

ChR2 activation of MeApd glutamatergic neurons did not alter c-Fos expression in the MPN relative to controls.

Results, Optogenetic excitation of VGluT2 neurons (data not shown)

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

MEA glutamatergic neurons nt-3kvfdzf7wn functionally connects to ARH (Arcuate hypothalamic nucleus) MBA:223 · Mouse

Optogenetic excitation of MeApd glutamatergic neurons did not change arcuate c-Fos counts.

Results, Optogenetic excitation of VGluT2 neurons (data not shown)

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

MEA glutamatergic neurons nt-3kvfdzf7wn projects to MPN (Medial preoptic nucleus) MBA:515 · Mouse

ChR2-tdTomato labelled fibers from MeApd glutamatergic neurons were present in the MPN, though they looked less prominent than the GABAergic innervation.

Fig. 3D; Results, AAV expression and fiber optic cannula placement

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

MEA glutamatergic neurons nt-3kvfdzf7wn functionally connects to VMH (Ventromedial hypothalamic nucleus) MBA:693 · Mouse

Photoexciting MeApd VGluT2 neurons produced no change in VMHvl c-Fos expression versus control mice.

Results, Optogenetic excitation of VGluT2 neurons (data not shown)

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

MEA glutamatergic neurons nt-3kvfdzf7wn projects to ARH (Arcuate hypothalamic nucleus) MBA:223 · Mouse

The arcuate nucleus lacked labelled fibers from MeApd glutamatergic neurons.

Fig. 3F; Results, AAV expression and fiber optic cannula placement

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.