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Journal article

Chronic Stress Induces Hepatic Steatosis via Brain-Hepatic Sympathetic Axis Mediated Catecholamine Resistance

International Journal of Biological Sciences, 2026

DOI 10.7150/ijbs.126058 · PubMed 41608627 · PMC12837740

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clm-7ffe2dmq9epresentretrograde tracerproposed

CEAm (Central amygdalar nucleus, medial part) MBA:559 projects to PVH (Paraventricular hypothalamic nucleus) MBA:38 · Mouse

A retrogradely transported Cre-expressing AAV was placed in the paraventricular hypothalamic nucleus together with a Cre-dependent hM4Di-mCherry vector in the medial central amygdala; mCherry-labelled cell bodies appeared in CeM, showing that CeM neurons send axons to PVH.

Fig. 8A, 8B; Results, 'CeM-PVH projections mediate chronic stress-induced hepatic lipid dysregulation'

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.