clm-0031dxd2sa

MD (Mediodorsal nucleus of thalamus) synapses onto BLA glutamatergic principal neurons

Species: Mouse
Result: present
Method: transsynaptic tracer
Sign: excitatory
Strength: strong
Evidence: Monosynaptic rabies tracing from CaMKII-Cre BLA starter cells labelled many neurons in the mediodorsal thalamus; these labelled cells colocalized with glutamate immunostaining and seldom with GABA.
Source: Distinct basolateral amygdala excitatory inputs mediate the somatosensory and aversive-affective components of pain
Journal of Biological Chemistry, 2022
DOI 10.1016/j.jbc.2022.102207 · PubMed 35772494 · PMC9304789, Fig. 4, F–I
Licence: CC-BY-4.0
Named in the paper: “MD (mediodorsal thalamic nucleus)” and “BLAGlu neurons”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-09
“Rabies tracing from BLA CaMKII starter cells labelled MD neurons that were glutamate-positive, as shown in Fig. 4F–I.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.