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CEA (Central amygdalar nucleus) projects to PAG (Periaqueductal gray)

All claims for this connection
Species
Mouse
Result
present
Method
retrograde tracer
Sign
unknown
Evidence
A Cre-dependent retrograde AAV expressing tdTomato was injected into the vlPAG of VGAT-Cre mice, and it labelled many GABAergic neurons in the central amygdala. About 85% of retrogradely labelled CeA neurons were tdTomato+, and about 15% of all labelled CeA neurons were double-labelled, meaning they also projected to the mPFC.
Source

Amygdala GABA Neurons Project To vlPAG And mPFC

IBRO Reports, 2019

DOI 10.1016/j.ibror.2019.03.001 · PubMed 31193158 · PMC6520332, Results; Fig. 3A-C; Table 1

Licence: CC-BY-NC-ND-4.0

Named in the paper
“CeA” and “vlPAG”
Made by
an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-09
Checked by

a second AI model (claude-opus-5) agrees, 2026-10-09

“Paper's Cre-dependent retrograde tdTomato from vlPAG labelled CeA neurons with the stated 85% and 15% figures.”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.