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PPN (Pedunculopontine nucleus) projects to DG (Dentate gyrus)

All claims for this connection
Species
Rat
Result
present
Method
retrograde tracer
Sign
unknown
Evidence
The pedunculopontine nucleus contained retrogradely labeled cells after the dentate gyrus tracer injection. Few or none were FOS-positive.
Source

The supramammillary nucleus and the claustrum activate the cortex during REM sleep

Science Advances, 2015

DOI 10.1126/sciadv.1400177 · PubMed 26601158 · PMC4640625, Results, 'Subcortical structures activating the cortex during REM sleep'
Named in the paper
“pedunculopontine nucleus” and “dentate gyrus”
Made by
an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-09
Checked by

a second AI model (claude-opus-5-5) agrees, 2026-10-09

“The Results state that every tracer injection, the dentate gyrus included, labeled pedunculopontine cells, with few or none FOS+.”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.