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CEAm (Central amygdalar nucleus, medial part) projects to PGRNl (Paragigantocellular reticular nucleus, lateral part)

All claims for this connection
Species
Mouse
Result
present
Method
retrograde tracer
Sign
unknown
Evidence
A retrogradely transported AAV carrying CRH-driven Cre was injected bilaterally into the LPGi together with a Cre-dependent DREADD virus in the CeM; mCherry-tagged receptor expression was then found in CeM neurons, showing that CeM cells send axons to the LPGi.
Source

A brain-tumor neural circuit controls breast cancer progression in mice

Journal of Clinical Investigation, 2023

DOI 10.1172/jci167725 · PubMed 37847562 · PMC10721160, Figs. 8A-C and 9A-C

Licence: CC-BY-4.0

Named in the paper
“CeM” and “LPGi”
Made by
an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by

a second AI model (claude-opus-5) agrees, 2026-10-09

“Retro-AAV-CRH-Cre in LPGi yielded Cre-dependent mCherry/DREADD expression in CeM neurons (Figs. 8A-C, 9A-C), supporting a CeM→LPGi projection shown by retrograde labeling.”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.