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CL:0000850 projects to ACA (Anterior cingulate area)

Species: Mouse
Result: present
Method: anterograde tracer
Sign: unknown
Evidence: In Pet-Cre x Ai32 mice, where ChR2-YFP is expressed only in serotonergic neurons, YFP-labelled axons that largely overlapped with SERT staining were seen in the cingulate gyrus of sham control mice. This labelling dropped after a left mPFC stroke and recovered with chronic fluoxetine.
Source: Fluoxetine-induced recovery of serotonin and norepinephrine projections in a mouse model of post-stroke depression
Translational Psychiatry, 2020
DOI 10.1038/s41398-020-01008-9 · PubMed 32999279 · PMC7527452, Fig. 2a; Results, Pet-ChR2 section
Licence: CC-BY-4.0
Named in the paper: “5-HT neurons (Pet-ChR2-YFP-expressing serotonergic neurons)” and “cingulate gyrus (CG) of the mPFC”
Made by: an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5-5) agrees, 2026-10-09
“Fig. 2a and the Pet-ChR2 results show YFP-labelled serotonergic axons, about 90% colocalized with SERT, in the mouse left cingulate gyrus; the signal fell after stroke and recovered with fluoxetine.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.