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CEA (Central amygdalar nucleus) functionally connects to PRNc (Pontine reticular nucleus, caudal part)

All claims for this connection
Species
Mouse
Result
present
Method
optogenetic circuit mapping
Sign
excitatory
Evidence
In PnC slices from GlyT2-Cre mice, blue-light stimulation of ChR2-expressing CeA fibres evoked facilitating EPSPs and EPSCs in tdTomato-labelled GlyT2+ neurons. AP5 and DNQX reduced these responses, and no light-evoked IPSCs appeared. Responsive cells lay medial to the 7th nerve or lateroventrally; midline and contralateral cells did not respond.
Measurements
  • connection probability: 0.47, n = 38
Source

The amygdala modulates prepulse inhibition of the auditory startle reflex through excitatory inputs to the caudal pontine reticular nucleus

BMC Biology, 2021

DOI 10.1186/s12915-021-01050-z · PubMed 34082731 · PMC8176709, Fig. 8-9

Licence: CC-BY-4.0

Named in the paper
“CamKIIα+ CeA excitatory neurons/fibers” and “GlyT2+ PnC neurons”
Made by
an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-09
Checked by

a second AI model (claude-opus-5-5) agrees, 2026-10-09

“Light-evoked facilitating EPSPs and EPSCs were blocked by AP5 and DNQX with no IPSCs, and 18 of 38 cells responded (about 0.47).”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.