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ORB (Orbital area) projects to ACA (Anterior cingulate area)

Species: Mouse
Result: present
Method: retrograde tracer
Sign: unknown
Strength: strong
Evidence: Orbital cortex contained densely labelled retrograde cells ipsilaterally and lightly labelled cells contralaterally after rACC injection; it was a major input, reduced in middle-aged versus young females.
Source: Afferent and efferent projections of the rostral anterior cingulate cortex in young and middle-aged mice
Frontiers in Aging Neuroscience, 2022
DOI 10.3389/fnagi.2022.960868 · PubMed 36062147 · PMC9428471, Fig. 2A, Fig. 3, Fig. 4A, Fig. 5B
Licence: CC-BY-4.0
Named in the paper: “orbital cortex (OC)” and “rACC”
Made by: an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-10
Checked by: a second AI model (claude-opus-5-5) agrees, 2026-10-10
“OC was dense ipsilaterally, light contralaterally and a major input, and was significantly lower in middle-aged than young females.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.