clm-4mv48n38b2
DR (Dorsal nucleus raphe) functionally connects to BLA glutamatergic principal neurons
All claims for this connection- Species
- Mouse
- Result
- present
- Method
- optogenetic circuit mapping
- Sign
- modulatory
- Evidence
- Thirty-second 20 Hz optical stimulation of raphe axons produced a slow outward current in nearly all basal amygdala principal neurons, reduced by the 5-HT1A antagonist WAY 100635 but not by GABA receptor blockers, and reduced the principal neurons' firing rate.
- Measurements
- connection probability: 0.93, n = 13
- Source
Control of Amygdala Circuits by 5-HT Neurons via 5-HT and Glutamate Cotransmission
The Journal of Neuroscience, 2017
DOI 10.1523/jneurosci.2238-16.2016 · PubMed 28087766 · PMC5320609, Fig. 5B–D,GLicence: CC-BY-NC-SA-4.0
- Named in the paper
- “DRN (5-HT neurons)” and “BA principal neurons (PNs)”
- Made by
- an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-10
- Checked by
a second AI model (claude-opus-5) agrees, 2026-10-10
“93% of BA PNs (n=13) showed a WAY 100635-sensitive slow IPSC and reduced firing with 20 Hz stimulation.”
- Status
proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.