clm-4zsw82gz7q

AI (Agranular insular area) projects to CNU (Cerebral nuclei)

Species: Mouse
Result: present
Method: retrograde tracer
Sign: unknown
Evidence: Retrograde Cre-dependent AAV injected into the IPAC of D1-cre mice also labelled D1-expressing neurons in the agranular insular cortex, though far fewer than in the mPFC.
Source: Social defeat stress-specific increase in c-Fos expression in the extended amygdala in mice: Involvement of dopamine D1 receptor in the medial prefrontal cortex
Scientific Reports, 2019
DOI 10.1038/s41598-019-52997-7 · PubMed 31723165 · PMC6854085, Fig. 4c; Results, 'D1-expressing mPFC pyramidal neurons send direct projections to the IPAC'
Licence: CC-BY-4.0
Named in the paper: “agranular insular cortex (AI)” and “interstitial nucleus of the posterior limb of the anterior commissure (IPAC)”
Made by: an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-09
“Paper reports EYFP-labelled neurons in AI after retrograde AAV injection in IPAC, though fewer than in mPFC.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.