clm-593b2m7etv

ARH (Arcuate hypothalamic nucleus) projects to PAG (Periaqueductal gray)

Species: Mouse
Result: present
Method: retrograde tracer
Sign: unknown
Strength: strong
Evidence: CTB injected into the PAG labeled many arcuate cells, including POMC neurons. The labeled POMC neurons tended to lie in the rostral arcuate, though this bias was not significant.
Source: Relative Number and Distribution of Murine Hypothalamic Proopiomelanocortin Neurons Innervating Distinct Target Sites
PLoS ONE, 2011
DOI 10.1371/journal.pone.0025864 · PubMed 21991375 · PMC3186811, Fig. 4C, Fig. 5B, Fig. 6B
Licence: CC-BY-4.0
Named in the paper: “arcuate nucleus (POMC neurons)” and “periaqueductal grey”
Made by: an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5-5) agrees, 2026-10-09
“PAG injections labeled many cells, and the rostral POMC bias was not significant (significance was reached only for DVC).”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.