clm-5es7qrw7m8

CP (Caudoputamen) projects to TH (Thalamus)

Species: Mouse
Result: present
Method: anterograde tracer
Sign: unknown
Evidence: Anterograde labelling from the dorsal striatum with AAV-hSyn-mCherry produced labelling in thalamic nuclei of wild-type and control mice; the labelling intensity fell to roughly half of wild-type values in dorsal-striatal CDK5 knockdown mice.
Source: Downregulation of CDK5 signaling in the dorsal striatum alters striatal microcircuits implicating the association of pathologies with circadian behavior in mice
Molecular Brain, 2022
DOI 10.1186/s13041-022-00939-2 · PubMed 35701839 · PMC9195255, Fig. 7A, B, E
Licence: CC-BY-4.0
Named in the paper: “dorsal striatum (DS)” and “thalamic nucleus (dorsal and ventral thalamic nuclei)”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-09
“Paper reports anterograde mCherry labeling from DS in thalamus with ~53% of WT intensity in KD mice.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.