clm-665gp1ggck

MEA (Medial amygdalar nucleus) projects to PVH (Paraventricular hypothalamic nucleus)

Species: Mouse
Result: present
Method: anterograde tracer
Sign: unknown
Evidence: Cre-dependent AAV carrying ChR2-EYFP injected into the posterodorsal medial amygdala of Ucn3-cre-tdTomato mice produced YFP-labelled axonal fibres within the hypothalamic paraventricular nucleus, showing that Ucn3 cells of the MePD send axons to the PVN; the authors note some fibres might reflect non-specific ChR2 expression.
Source: Posterodorsal Medial Amygdala Urocortin-3, GABA, and Glutamate Mediate Suppression of LH Pulsatility in Female Mice
Endocrinology, 2022
DOI 10.1210/endocr/bqac196 · PubMed 36445688 · PMC9761574, Fig. 5, A-Aiii; Results, final section
Licence: CC-BY-NC-ND-4.0
Named in the paper: “MePD Ucn3 neurons” and “paraventricular nucleus of hypothalamus (PVN)”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-09
“Cre-dependent AAV-ChR2-EYFP from MePD labeled fibers in PVN, as described in the results and Fig. 5 caption.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.