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CA1 (Field CA1) projects to ORB (Orbital area)

All claims for this connection
Species
Mouse
Result
present
Method
retrograde tracer
Sign
unknown
Evidence
AAV2/retro-EGFP injected into the OFC of C57 mice retrogradely labelled neurons in ventral CA1, indicating a direct monosynaptic vCA1 to OFC projection.
Source

Distinct orbitofrontal circuits with dorsal and ventral CA1 differentially regulate spatial memory and emotional behaviors

Frontiers in Behavioral Neuroscience, 2026

DOI 10.3389/fnbeh.2026.1853168 · PubMed 42358617 · PMC13290759, Fig. 2Q–T

Licence: CC-BY-4.0

Named in the paper
“vCA1” and “OFC”
Made by
an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-10
Checked by

a second AI model (claude-opus-5-5) agrees, 2026-10-10

“Fig. 2Q–T shows retrograde EGFP labelling in vCA1 from an OFC injection in C57 mice, read as a direct projection.”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.