clm-7cz07e4m81

BLAp (Basolateral amygdalar nucleus, posterior part) functionally connects to BST (Bed nuclei of the stria terminalis)

Species: Mouse
Result: present
Method: optogenetic circuit mapping
Sign: inhibitory
Evidence: Although posterior BLA terminals produced monosynaptic excitatory currents in adBNST neurons, the disynaptic GABAergic currents they recruited were larger, giving a high inhibition/excitation ratio and a net suppression of adBNST firing that was reversed by GABA-A receptor blockade; chemogenetic activation of pBLA to dBNST neurons likewise lowered adBNST calcium signals in vivo.
Source: Synergism between two BLA-to-BNST pathways for appropriate expression of anxiety-like behaviors in male mice
Nature Communications, 2024
DOI 10.1038/s41467-024-47966-2 · PubMed 38658548 · PMC11043328, Fig. 2h–j; Fig. 3c, e, f; Supplementary Fig. 3, 5
Licence: CC-BY-4.0
Named in the paper: “pBLA” and “adBNST”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-09
“Net suppression of adBNST firing with high I/E ratio, GABA-dependent, confirmed in vivo.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.