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BLAp (Basolateral amygdalar nucleus, posterior part) functionally connects to BST (Bed nuclei of the stria terminalis)

2 claims from 1 source: 2 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-3246dg8v5rpresentoptogenetic circuit mappingproposed

Optogenetic stimulation of posterior BLA terminals strongly increased firing of oval BNST neurons and evoked robust excitatory (and inhibitory) postsynaptic currents there, consistent with the dense terminal field.

DOI 10.1038/s41467-024-47966-2 · PubMed 38658548 · PMC11043328, Fig. 2e–g; Supplementary Fig. 4a–d

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

clm-7cz07e4m81presentoptogenetic circuit mappingproposed

Although posterior BLA terminals produced monosynaptic excitatory currents in adBNST neurons, the disynaptic GABAergic currents they recruited were larger, giving a high inhibition/excitation ratio and a net suppression of adBNST firing that was reversed by GABA-A receptor blockade; chemogenetic activation of pBLA to dBNST neurons likewise lowered adBNST calcium signals in vivo.

DOI 10.1038/s41467-024-47966-2 · PubMed 38658548 · PMC11043328, Fig. 2h–j; Fig. 3c, e, f; Supplementary Fig. 3, 5

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.