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CEAl somatostatin-expressing neurons functionally connects to CEAl (Central amygdalar nucleus, lateral part)

All claims for this connection
Species
Mouse
Result
present
Method
optogenetic circuit mapping
Sign
inhibitory
Evidence
Single-cell two-photon activation of CeL SOM+ neurons evoked IPSCs in patched SOM− neurons: 160 of 681 activated cells were connected in wild-type mice and 63 of 557 in SOM-PTEN-KO mice. IPSCs were also smaller in the knockout.
Measurements
  • connection probability: 0.2349, n = 681
Source

PTEN in somatostatin neurons regulates fear and anxiety and is required for inhibitory synaptic connectivity within central amygdala

Frontiers in Cellular Neuroscience, 2025

DOI 10.3389/fncel.2025.1597131 · PubMed 40642101 · PMC12240933, Fig. 3k; Fig. 4c; Results 2.4

Licence: CC-BY-4.0

Named in the paper
“SOM+ neurons (CeL)” and “SOM− neurons in CeL”
Made by
an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-10
Checked by

a second AI model (claude-opus-5-5) agrees, 2026-10-10

“Fig. 3k and Results 2.4 report wild-type SOM+ to SOM− connectivity of 160 of 681 (23.49%), with IPSCs isolated under glutamate blockade, and Fig. 4c shows smaller knockout currents.”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.