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CEAl (Central amygdalar nucleus, lateral part) functionally connects to CEAl somatostatin-expressing neurons

All claims for this connection
Species
Mouse
Result
present
Method
optogenetic circuit mapping
Sign
inhibitory
Evidence
Photoactivating single tdTomato-negative (SOM−) CeL neurons produced IPSCs in patched SOM+ neurons. In wild-type mice 107 of 204 activated cells were connected, and connectivity fell to 73 of 333 in SOM-PTEN-KO mice.
Measurements
  • connection probability: 0.5245, n = 204
Source

PTEN in somatostatin neurons regulates fear and anxiety and is required for inhibitory synaptic connectivity within central amygdala

Frontiers in Cellular Neuroscience, 2025

DOI 10.3389/fncel.2025.1597131 · PubMed 40642101 · PMC12240933, Fig. 3i; Fig. 4b; Results 2.4

Licence: CC-BY-4.0

Named in the paper
“SOM− neurons in CeL” and “SOM+ neurons (CeL)”
Made by
an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-10
Checked by

a second AI model (claude-opus-5-5) agrees, 2026-10-10

“Results 2.4 and Fig. 3i give wild-type SOM− to SOM+ connectivity of 107 of 204 (52.45%), falling to 73 of 333 in knockouts, measured as IPSCs by two-photon mapping.”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.