clm-8bn1cs52qe

Rat central amygdala corticotropin-releasing hormone-expressing neurons projects to LC (Locus ceruleus)

Species: Rat
Result: present
Method: retrograde tracer
Sign: unknown
Evidence: Some CNA neurons retrogradely labeled with Fluorogold from the LC were also CRF-immunoreactive. Triple-labeled cells (FG, CRF and c-fos) were identified in the CNA.
Source: Social Stress Engages Neurochemically-Distinct Afferents to the Rat Locus Coeruleus Depending on Coping Strategy
eneuro, 2015
DOI 10.1523/eneuro.0042-15.2015 · PubMed 26634226 · PMC4660134, Results, 'Repeated social stress-induced activation of LC-projecting CRF neurons in the CNA'; Fig. 3
Named in the paper: “CRF-immunolabeled LC-projecting neurons in the CNA” and “locus coeruleus (LC)”
Made by: an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5-5) agrees, 2026-10-09
“The Results and Fig. 3 report CNA neurons labeled for Fluorogold, CRF and c-fos, showing CRF neurons project to the LC.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.