clm-8vq0k5xgfp

PB (Parabrachial nucleus) functionally connects to CEAl somatostatin-expressing neurons

Species: Mouse
Result: present
Method: optogenetic circuit mapping
Sign: excitatory
Evidence: Optogenetic activation of parabrachial axons in TTX/4-AP elicited monosynaptic EPSCs in somatostatin-expressing lateral-division central amygdala neurons; amplitude (about 100 pA) and paired-pulse ratio (about 0.41) did not differ from neighbouring SOM-negative cells in 11 sequentially recorded pairs.
Source: Spared nerve injury differentially alters parabrachial monosynaptic excitatory inputs to molecularly specific neurons in distinct subregions of the central amygdala
Pain, 2019
DOI 10.1097/j.pain.0000000000001691 · PubMed 31479066 · PMC6940027, Fig. 3A–C; Results 3.2
Licence: CC-BY-NC-ND-4.0
Named in the paper: “PBn” and “SOM+ CeL neurons”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5-5) agrees, 2026-10-09
“SOM+ CeL neurons showed monosynaptic EPSCs of about 100 pA with PPR about 0.41, not different from SOM− cells in 11 pairs.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.