Skip to content

clm-9ckwc4yfq3

SSp-ll (Primary somatosensory area, lower limb) synapses onto BLA (Basolateral amygdalar nucleus)

All claims for this connection
Species
Mouse
Result
present
Method
transsynaptic tracer
Sign
unknown
Evidence
Anterograde transsynaptic AAV2/1-hSyn-Cre placed in S1HL combined with Cre-dependent AAV-DIO-EGFP in BLA labelled numerous BLA postsynaptic neurons; about 90% of the labelled BLA cells expressed CCK mRNA and about 83% expressed Slc17a7 mRNA, identifying them as CCK-positive glutamatergic neurons.
Measurements
  • fraction of labelled neurons: 0.9001 (SEM 0.0644)
  • fraction of labelled neurons: 0.8338 (SEM 0.0662)
Source

The primary somatosensory sensory cortex-basolateral amygdala pathway contributes to comorbid depression in spared nerve injury-induced neuropathic pain

Scientific Reports, 2025

DOI 10.1038/s41598-025-97164-3 · PubMed 40258918 · PMC12012082, Fig. 3C1-C3, 3D, 3E

Licence: CC-BY-NC-ND-4.0

Named in the paper
“S1HL” and “BLA”
Made by
an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by

a second AI model (claude-opus-5) agrees, 2026-10-09

“Anterograde transsynaptic Cre/DIO-EGFP labelling in BLA with the stated CCK (90.01±6.44%) and Slc17a7 (83.38±6.62%) percentages matches Fig. 3C-E.”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.