clm-9tyxc9gd9w

ILA (Infralimbic area) functionally connects to BLA (basal amygdaloid nucleus)

Species: Rat
Result: present
Method: optogenetic circuit mapping
Sign: excitatory
Evidence: Photostimulation of ChR2-expressing IL axons in slices evoked EPSCs and IPSCs in BLA neurons; unlike the CeLC, these amplitudes and their ratio were unchanged by opioid-induced hyperalgesia.
Source: Projections from infralimbic medial prefrontal cortex glutamatergic outputs to amygdala mediates opioid induced hyperalgesia in male rats
Molecular Pain, 2024
DOI 10.1177/17448069241226960 · PubMed 38172075 · PMC10851759, Sup. Figure 2
Licence: CC-BY-NC-4.0
Named in the paper: “IL” and “BLA”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-09
“The text states IL-evoked EPSCs/IPSCs were recorded in BLA and were unaffected by OIH, with the data in Sup. Figure 2.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.