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CBX (Cerebellar cortex) functionally connects to CL:0000121

All claims for this connection
Species
Mouse
Result
present
Method
optogenetic circuit mapping
Sign
inhibitory
Evidence
In cerebellar slices from nNOS-ChR2 mice, 8 Hz light trains raised action-potential frequency in molecular layer interneurons and simultaneously lowered the firing rate of downstream Purkinje cells while increasing the irregularity of their spiking, consistent with GABAergic inhibition of Purkinje cells by these interneurons.
Named in the paper
“molecular layer interneurons (MLIs) in cerebellar vermis” and “Purkinje cells (PCs)”
Made by
an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by

a second AI model (claude-opus-5-5) agrees, 2026-10-09

“Photostimulating MLIs raised their firing and lowered PC firing while increasing its CV, consistent with inhibition.”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.