clm-a38wage5x6

PB (Parabrachial nucleus) functionally connects to CEA (Central amygdalar nucleus)

Species: Mouse
Result: present
Method: electrical stimulation
Sign: excitatory
Evidence: Stimulating the fiber bundle of LPB origin running dorsomedial to the CeA evoked short-latency excitatory postsynaptic currents in CeC/L neurons recorded at -70 mV; these responses were larger in formalin-treated than saline-treated mice and, unlike BLA-evoked responses, were unaffected by pregabalin. Both LPB- and BLA-evoked EPSCs could be recorded in the same CeC/L neurons, showing convergence of the two inputs.
Source: Input-dependent synaptic suppression by pregabalin in the central amygdala in male mice with inflammatory pain
Neurobiology of Pain, 2021
DOI 10.1016/j.ynpai.2021.100078 · PubMed 34877437 · PMC8628014, Figs. 1B, 4, 5; Results
Licence: CC-BY-4.0
Named in the paper: “LPB (lateral parabrachial nucleus)” and “CeC/L (capsular and lateral part of the central nucleus of the amygdala)”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5-5) agrees, 2026-10-09
“Stimulating the putative LPB-derived fibers evoked EPSCs in CeC/L neurons that were larger after formalin and insensitive to pregabalin, and both inputs were recorded in the same neurons in Fig. 5.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.