clm-a6jp4vtb3d
MEA (Medial amygdalar nucleus) functionally connects to ARH (Arcuate hypothalamic nucleus)
All claims for this connection- Species
- Mouse
- Result
- present
- Method
- optogenetic circuit mapping
- Sign
- unknown
- Evidence
- Selective 10 Hz activation of MePD UCN3 neurons that do not express GABA increased the LH inter-pulse interval (15.47 ± 0.91 min before versus 23.75 ± 1.07 min during stimulation, n = 6), with no change in no-stimulation or control-virus groups; the same stimulation combined with optogenetic silencing of non-UCN3 MePD GABA neurons no longer altered LH pulse interval, indicating the effect on the pulse generator requires MePD GABA neurons.
- Source
The role of amygdala GABA neurons in controlling stress and reproduction in female mice
Nature Communications, 2026
DOI 10.1038/s41467-026-70364-9 · PubMed 41807404 · PMC13319269, Fig. 5A–D; Fig. 6H–JLicence: CC-BY-4.0
- Named in the paper
- “MePD UCN3 non-GABA neurons (Con/Foff ChRmine)” and “hypothalamic GnRH pulse generator (arcuate KNDy network)”
- Made by
- an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
- Checked by
a second AI model (claude-opus-5) agrees, 2026-10-09
“LH IPI values, n, and the loss of the effect when non-UCN3 GABA neurons were silenced match the reported results.”
- Status
proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.