clm-ahp17bd3ye

ORBm (Orbital area, medial part) projects to MD (Mediodorsal nucleus of thalamus)

Species: Mouse
Result: present
Method: anterograde tracer
Sign: unknown
Evidence: Cre-dependent mGFP and synaptophysin-mRuby expressed in CaMKIIα+ mOFC neurons of CaMKII-Cre mice labelled axons with colocalized presynaptic puncta in the mediodorsal thalamus.
Source: The medial orbitofrontal cortex mediates neuropathic pain and anxiodepressive-like behaviors via two distinct pathways
The Journal of Headache and Pain, 2026
DOI 10.1186/s10194-026-02335-w · PubMed 41851827 · PMC13112918, Fig. 4A-C
Licence: CC-BY-4.0
Named in the paper: “mOFC” and “MD (mediodorsal thalamus)”
Made by: an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5-5) agrees, 2026-10-09
“The anterograde tracing figure shows labelled fibers colocalized with presynaptic puncta in the MD (Fig. 4C).”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.