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AI (Agranular insular area) projects to CP (Caudoputamen)

Species: Mouse
Result: present
Method: retrograde tracer
Sign: unknown
Evidence: Following caudate putamen injection of the retrograde AAV, transgene-expressing neurons appeared in insular cortex, notably in its fifth layer, matched by localized hypointense MRI contrast and significant T2 relaxation-time changes.
Source: Longitudinal neural connection detection using a ferritin‐encoding adeno‐associated virus vector and in vivo MRI method
Human Brain Mapping, 2021
DOI 10.1002/hbm.25596 · PubMed 34288264 · PMC8449107, Figs. 1b, 2b, 4, 6; Results
Licence: CC-BY-NC-ND-4.0
Named in the paper: “Ins (insular cortex)” and “CPu”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-09
“Insular cortex (layer 5) labeling after retrograde AAV in CPu is reported in fluorescence and MRI.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.