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SUB (Subiculum) projects to ACB (Nucleus accumbens)

All claims for this connection
Species
Mouse
Result
present
Method
retrograde tracer
Sign
unknown
Evidence
A retrogradely transported AAV2/5-CaMKIIa-EYFP vector injected into the nucleus accumbens labelled EYFP-positive neurons in ventral hippocampus, which were then assessed for EGR1 immunoreactivity, demonstrating vHIP neurons that project to NAc.
Source

Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression

Nature Communications, 2015

DOI 10.1038/ncomms8062 · PubMed 25952660 · PMC4430111, Fig. 1g,h; Methods (Stereotaxic surgery and viral vectors)

Licence: CC-BY-4.0

Named in the paper
“vHIP (ventral subiculum)” and “NAc”
Made by
an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by

a second AI model (claude-opus-5) agrees, 2026-10-09

“Retrogradely labelled vHIP (ventral subiculum target) neurons from NAc injection are shown in Fig. 1g,h.”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.