clm-brb4ne165n

Isocortex projects to CP (Caudoputamen)

Species: Mouse
Result: present
Method: retrograde tracer
Sign: unknown
Evidence: After injecting the retrogradely transported rAAV2-retro vector (ferritin- or EGFP-encoding) into the caudate putamen, labelled cell bodies expressing the transgene were seen in prefrontal cortex, both by fluorescence/immunostaining and as hypointense T2-weighted MRI signal and significant T2 relaxation-time changes that grew from 30 to 60 days post-injection.
Source: Longitudinal neural connection detection using a ferritin‐encoding adeno‐associated virus vector and in vivo MRI method
Human Brain Mapping, 2021
DOI 10.1002/hbm.25596 · PubMed 34288264 · PMC8449107, Figs. 1b, 2b, 4, 5, 6; Results
Licence: CC-BY-NC-ND-4.0
Named in the paper: “PFC (prefrontal cortex)” and “CPu”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-09
“PFC labeling after CPu retrograde AAV injection is reported, though the ontology ID is a coarse isocortex parent.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.