clm-c62p4q5pfg
ILA (Infralimbic area) functionally connects to ACB (Nucleus accumbens)
All claims for this connection- Species
- Mouse
- Result
- present
- Method
- optogenetic circuit mapping
- Sign
- excitatory
- Evidence
- Optical stimulation of ChR2-expressing mPFC axon terminals in NAc shell slices evoked EPSCs in medium spiny neurons, with paired-pulse responses and reliable responses to 1 Hz and 4 Hz light trains, consistent with a glutamatergic mPFC input to NAc.
- Source
Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression
Nature Communications, 2015
DOI 10.1038/ncomms8062 · PubMed 25952660 · PMC4430111, Fig. 1o,p; Fig. 2c; Fig. 3cLicence: CC-BY-4.0
- Named in the paper
- “mPFC (infralimbic prefrontal cortex)” and “NAc shell”
- Made by
- an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
- Checked by
a second AI model (claude-opus-5) agrees, 2026-10-09
“ChR2 stimulation of mPFC terminals evoked EPSCs in NAc shell MSNs in the cited panels.”
- Status
proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.