clm-dvxpwhpwmq

PVT (Paraventricular nucleus of the thalamus) synapses onto CEA (Central amygdalar nucleus)

Species: Mouse
Result: present
Method: transsynaptic tracer
Sign: unknown
Evidence: Anterograde transsynaptic Cre injected in the pPVT labelled postsynaptic cell bodies in the central amygdala of Ai9 mice; a second experiment with transsynaptic Flp from the pPVT combined with a Cre/Flp-dependent vector in VGAT-Cre mice selectively labelled CeA GABAergic neurons receiving pPVT input.
Source: The pPVTglu- CeAGABA circuit is involved in regulating hyperalgesia in the chronic NTG mouse model in males
The Journal of Headache and Pain, 2026
DOI 10.1186/s10194-026-02285-3 · PubMed 41652327 · PMC12977853, Fig. 3C-D; Fig. 7G-I
Licence: CC-BY-NC-ND-4.0
Named in the paper: “pPVT” and “CeA”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-09
“Both transsynaptic experiments support pPVT synapsing onto CeA neurons.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.