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CEA (Central amygdalar nucleus) functionally connects to ZI (Zona incerta)
All claims for this connection- Species
- Mouse
- Result
- present
- Method
- optogenetic circuit mapping
- Sign
- inhibitory
- Evidence
- After ChR2-EYFP expression in central amygdala neurons, blue-light stimulation of their terminals in the zona incerta evoked monosynaptic (TTX/4-AP resistant) inhibitory postsynaptic currents in 12 of 20 VGAT-positive zona incerta neurons; the currents were reduced by the GABA-A antagonist bicuculline and absent or small near the chloride reversal potential.
- Measurements
- connection probability: 0.6, n = 20
- Source
An inhibitory circuit from central amygdala to zona incerta drives pain-related behaviors in mice
eLife, 2022
DOI 10.7554/elife.68760 · PubMed 36269044 · PMC9635874, Figure 2C-FLicence: CC0-1.0
- Named in the paper
- “CeA” and “ZI (VGAT-positive neurons)”
- Made by
- an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-10
- Checked by
a second AI model (claude-opus-5) agrees, 2026-10-10
“12/20 VGAT-positive ZI neurons showed monosynaptic, bicuculline-sensitive oIPSCs from CeA terminals.”
- Status
proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.