Mouse

CEA (Central amygdalar nucleus) functionally connects to ZI (Zona incerta)

2 claims from 1 source: 2 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-0dc62czm14presentoptogenetic circuit mappingproposed

Optical stimulation of ChR2-expressing central amygdala terminals also elicited inhibitory postsynaptic currents in 8 of 15 VGAT-negative zona incerta neurons, with paired-pulse ratios indistinguishable from those of VGAT-positive cells.

DOI 10.7554/elife.68760 · PubMed 36269044 · PMC9635874, Figure 2D

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

clm-f2kagndczmpresentoptogenetic circuit mappingproposed

After ChR2-EYFP expression in central amygdala neurons, blue-light stimulation of their terminals in the zona incerta evoked monosynaptic (TTX/4-AP resistant) inhibitory postsynaptic currents in 12 of 20 VGAT-positive zona incerta neurons; the currents were reduced by the GABA-A antagonist bicuculline and absent or small near the chloride reversal potential.

DOI 10.7554/elife.68760 · PubMed 36269044 · PMC9635874, Figure 2C-F

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.