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MEA (medial amygdaloid nucleus) projects to LZ (Hypothalamic lateral zone)

Species: Rat
Result: present
Method: retrograde tracer
Sign: unknown
Evidence: After CTb injection into the perifornical region, retrogradely labelled neurons appeared in the ipsilateral amygdala, with labelled cells (especially seizure-activated ones) concentrated in medial subnuclei including MeA. About 56% of Fos+ neurons were CTb co-labelled in seizure rats versus about 11% in controls.
Source: Selective activation of the hypothalamic orexinergic but not melanin-concentrating hormone neurons following pilocarpine-induced seizures in rats
Frontiers in Neuroscience, 2022
DOI 10.3389/fnins.2022.1056706 · PubMed 36532270 · PMC9751402, Fig. 5A,D; Results, 'Amygdala neurons might transmit epileptic activity...'
Licence: CC-BY-4.0
Named in the paper: “medial amygdaloid nucleus (MeA)” and “perifornical nucleus”
Made by: an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-10
Checked by: a second AI model (claude-opus-5-5) disagrees, 2026-10-10
“The 56% vs 11% co-labelling figures are for amygdala neurons overall after perifornical injection, not for MeA specifically.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.