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MGm (Medial geniculate complex, medial part) functionally connects to LA glutamatergic principal neurons
All claims for this connection- Species
- Mouse
- Result
- present
- Method
- optogenetic circuit mapping
- Sign
- excitatory
- Evidence
- Light pulses applied to ChR2-expressing thalamic axons within the LA evoked EPSCs in LA pyramidal cells; when only MGm was infected, 89% of recorded LA pyramidal neurons responded (84% with combined MGm+AuV infection, N = 50 cells). The responses were abolished by the broad glutamate receptor antagonist kynurenic acid in slices and reduced to ~15% of control by in vivo kynurenic acid infusion. In vivo, photostimulation of MGm produced field potentials in LA with a 12-ms latency.
- Measurements
- connection probability: 0.89
- conduction delay: 12 ms
- Source
Optogenetic activation of presynaptic inputs in lateral amygdala forms associative fear memory
Learning & Memory, 2014
DOI 10.1101/lm.035816.114 · PubMed 25322798 · PMC4201812, Fig. 2A (bottom), Fig. 2B, Fig. 4A; Results, sections 2 and 4- Named in the paper
- “MGm” and “LA pyramidal neurons”
- Made by
- an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
- Checked by
a second AI model (claude-opus-5) agrees, 2026-10-09
“MGm-only infection yielded EPSCs in 89% of LA pyramidal neurons, blocked by kynurenic acid, with ~12 ms LA field-potential latency in vivo.”
- Status
proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.