Mouse

MGm (Medial geniculate complex, medial part) functionally connects to LA glutamatergic principal neurons

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-g7vknq0ahypresentoptogenetic circuit mappingproposed

Light pulses applied to ChR2-expressing thalamic axons within the LA evoked EPSCs in LA pyramidal cells; when only MGm was infected, 89% of recorded LA pyramidal neurons responded (84% with combined MGm+AuV infection, N = 50 cells). The responses were abolished by the broad glutamate receptor antagonist kynurenic acid in slices and reduced to ~15% of control by in vivo kynurenic acid infusion. In vivo, photostimulation of MGm produced field potentials in LA with a 12-ms latency.

DOI 10.1101/lm.035816.114 · PubMed 25322798 · PMC4201812, Fig. 2A (bottom), Fig. 2B, Fig. 4A; Results, sections 2 and 4

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); not checked yet.