clm-jh3jx43xbv

PVT (Paraventricular nucleus of the thalamus) projects to ACB (Nucleus accumbens)

Species: Mouse
Result: present
Method: anterograde tracer
Sign: unknown
Evidence: A Cre-dependent anterograde tracer expressing mGFP and synaptophysin-mRuby was injected into the pPVT of Vglut2-Cre mice; mRuby-labelled axon terminals from pPVT glutamatergic neurons were seen in the nucleus accumbens three weeks later.
Source: The pPVTglu- CeAGABA circuit is involved in regulating hyperalgesia in the chronic NTG mouse model in males
The Journal of Headache and Pain, 2026
DOI 10.1186/s10194-026-02285-3 · PubMed 41652327 · PMC12977853, Fig. 3A-B
Licence: CC-BY-NC-ND-4.0
Named in the paper: “pPVT” and “NAc”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-09
“Matches the anterograde tracing result in NAc.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.