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PPN (Pedunculopontine nucleus) projects to RSP (Retrosplenial area)

All claims for this connection
Species
Rat
Result
present
Method
retrograde tracer
Sign
unknown
Evidence
The pedunculopontine nucleus contained retrogradely labeled cells after the retrosplenial tracer injection. Few were FOS-positive.
Source

The supramammillary nucleus and the claustrum activate the cortex during REM sleep

Science Advances, 2015

DOI 10.1126/sciadv.1400177 · PubMed 26601158 · PMC4640625, Results, 'Subcortical structures activating the cortex during REM sleep'
Named in the paper
“pedunculopontine nucleus” and “retrosplenial cortex”
Made by
an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-09
Checked by

a second AI model (claude-opus-5-5) agrees, 2026-10-09

“The pedunculopontine nucleus is listed as labeled after all injections, the retrosplenial included.”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.