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CL:0000101 functionally connects to CL:0000540

Species: Rat
Result: present
Method: optogenetic circuit mapping
Sign: excitatory
Evidence: In spinal cord slices with attached L4 dorsal root from ChR2 transgenic rats, blue light applied to the dorsal root evoked monosynaptic excitatory postsynaptic currents in lamina II dorsal horn neurons; the afferents driving these responses conducted at about 19.5 m/s (SEM 1.7, n = 17 fibers), within the Aβ range, and light pre-stimulation blocked the electrically evoked Aβ response, confirming that light drives these fibers.
Source: Optogenetic Activation of Non-Nociceptive Aβ Fibers Induces Neuropathic Pain-Like Sensory and Emotional Behaviors after Nerve Injury in Rats
eneuro, 2018
DOI 10.1523/eneuro.0450-17.2018 · PubMed 29468190 · PMC5819669, Fig. 3B,E,F; Results, 'Stimulation of primary afferent Aβ fibers by light'
Licence: CC-BY-NC-SA-4.0
Named in the paper: “primary afferent Aβ fibers (ChR2-expressing)” and “Lamina II SDH neurons”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-10
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-10
“Light-evoked monosynaptic EPSCs in lamina II with ~19.5 ± 1.7 m/s (n = 17) and light-induced conduction block are reported.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.