clm-kb7szsn2wm

CEA (Central amygdalar nucleus) projects to PAG (Periaqueductal gray)

Species: Mouse
Result: present
Method: anterograde tracer
Sign: unknown
Strength: strong
Evidence: Anterograde labelling from Cre-dependent tdTomato-tagged opsin expression in NPY2R-positive CeA neurons revealed labelled axons in the ventrolateral periaqueductal gray.
Source: Activation of NPY2R-expressing amygdala neurons inhibits itch behavior in mice without lateralization
Scientific Reports, 2024
DOI 10.1038/s41598-024-73483-9 · PubMed 39333236 · PMC11437048, Fig. 6B; Results, projection tracing section
Licence: CC-BY-NC-ND-4.0
Named in the paper: “NPY2R+ CeA neurons (central nucleus of the amygdala)” and “ventrolateral periaqueductal gray (vlPAG)”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-09
“vlPAG labelling is reported in Results and Fig. 6B; PAG parent term is acceptable.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.